We are studying a new medication to treat Anemia associated with Chronic Kidney Disease. If you currently suffer from Chronic Kidney Disease, (CKD) Stage 3, 4, or 5 and are not on dialysis, you may qualify for this trial of a unique oral medication to improve anemia. The dose of medication will be individualized to your need, and the average response to the medication is 28 days. In the study, you may remain on maintenance dose for at least a year. Participants will receive the investigational medication, study-related medical exams and lab tests at no charge. You may also be provided with compensation for your time and travel.